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About EPERISONE+PARACETAMOL

EPERISONE+PARACETAMOL belongs to the class of medications called antispasmodics combined with a painkiller used to treat muscle spasms. Muscle spasm is the sudden painful and involuntary muscle contractions, which occur when the nerve impulses that control the muscle movements are damaged or interrupted. It is characterized by muscle tightness, joint stiffness, unusual posture, difficulty moving, and pain in affected muscles and joints.

EPERISONE+PARACETAMOL is a combination of two drugs: Eperisone (muscle relaxant) and Paracetamol (pain killer). Eperisone works by relaxing skeletal muscles and reducing myotonia (inability of muscles to relax). It can relax vascular smooth muscles (smooth muscle found in the wall of blood vessels) and improve blood circulation. It can also suppress pain reflexes. These effects of EPERISONE+PARACETAMOL help to reduce pain and spasms in the muscle effectively. Paracetamol is an analgesic (pain reliever) and an antipyretic (fever reducer). It inhibits cyclo-oxygenase (COX) enzymes that further prevent the formation of chemical messengers called 'prostaglandins' (PGs). These prostaglandins are produced at injury sites and cause pain and swelling. By blocking the COX enzyme's effect, lesser PGs are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site. Collectively, EPERISONE+PARACETAMOL helps to reduce pain and spasms in the muscle effectively.

You should take this medicine exactly as prescribed by your doctor. The common side effects of EPERISONE+PARACETAMOL are nausea, vomiting, stomach discomfort, headache, weakness, drowsiness, and dizziness. Most of these side effects are mild and temporary. However, inform your doctor immediately if any of these side effects persist or get worse.

Before starting EPERISONE+PARACETAMOL, please inform your doctor if you have any known allergy EPERISONE+PARACETAMOL, heart, kidney, and liver problems. Consult your doctor before taking EPERISONE+PARACETAMOL if you are pregnant or planning for pregnancy. Do not take EPERISONE+PARACETAMOL if you are breastfeeding. EPERISONE+PARACETAMOL is not recommended for use in children. Elderly patients may require dose adjustments. EPERISONE+PARACETAMOL may cause dizziness, so drive only if you are alert. Avoid consuming alcohol along with EPERISONE+PARACETAMOL as it could lead to increased dizziness and risk of liver damage.

Uses of EPERISONE+PARACETAMOL

Muscle spasm

Medicinal Benefits

EPERISONE+PARACETAMOL is a combination of two drugs, namely; Eperisone (muscle relaxant) and Paracetamol (painkiller). Eperisone is a muscle relaxant with an analgesic effect. It reduces muscle stiffness and spasticity, enabling the movement of muscles easily. It can be used during rehabilitation (restoring functional ability in people with physical disabilities) as it can allow voluntary movement of the upper and lower extremities without using muscle power. On the other hand, Paracetamol is an analgesic (pain reliever) and an antipyretic (fever reducer). It inhibits cyclo-oxygenase (COX) enzymes that further prevent the formation of chemical messengers called 'prostaglandins' (PGs). These prostaglandins are produced at injury sites and cause pain and swelling. By blocking the COX enzyme's effect, lesser PGs are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site. Together, EPERISONE+PARACETAMOL helps in relieving pain due to muscle spasms.

Directions for Use

Take EPERISONE+PARACETAMOL as advised by the doctor. Swallow it as a whole with a glass of water. Do not crush, chew, or break it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of EPERISONE+PARACETAMOL

  • Nausea
  • Vomiting
  • Stomach discomfort
  • Headache
  • Weakness
  • Drowsiness
  • Dizziness

In-Depth Precautions and Warning

Drug Warnings

Do not take EPERISONE+PARACETAMOL if you have any known allergies to eperisone and paracetamol. EPERISONE+PARACETAMOL may cause liver damage, so it should be used cautiously in patients with liver diseases. Please consult your doctor to know if you are pregnant and planning to conceive. Do not take EPERISONE+PARACETAMOL if you are breastfeeding. Use EPERISONE+PARACETAMOL with caution in elderly patients; elder adults above 60 years may have increased drowsiness, confusion, and a higher risk of falling while taking EPERISONE+PARACETAMOL. EPERISONE+PARACETAMOL is not recommended in children as safety and effectiveness have not been established. People who are dehydrated for a long time should avoid the intake of EPERISONE+PARACETAMOL. If you notice dizziness, sleepiness, and weakness, you should refrain from activities that require you to stay alert such as driving or operating heavy machinery. Also, inform your doctor if these effects are persistent or worse, the doctor may make dose adjustments based on the severity of side-effects. Let your doctor know if you use any prescription and non-prescription medications you are taking, including other vitamins, before starting EPERISONE+PARACETAMOL.

Drug Interactions

Drug-Drug Interactions: EPERISONE+PARACETAMOL may interact with a muscle relaxant (methocarbamol),  blood thinners (warfarin), lipid-lowering drugs (cholestyramine), analgesics (ibuprofen, aspirin), muscle relaxants (tizanidine), and anti-nausea agents (metoclopramide or domperidone).

Drug-Food Interactions: Avoid foods containing alcohol, caffeine such as coffee, tea, chocolate or cola.

Drug-Disease Interactions: EPERISONE+PARACETAMOL should be used with caution in patients with hepatic failure (liver diseases), chronic alcoholism, cardiac diseases (heart problems), hypertension, peptic ulcer, and renal dysfunction (kidney diseases) should use EPERISONE+PARACETAMOL with caution.

Drug-Drug Interactions Checker List:

  • METHOCARBAMOL
  • WARFARIN
  • CHOLESTYRAMINE
  • IBUPROFEN
  • ASPIRIN
  • TIZANIDINE
  • METOCLOPRAMIDE
  • DOMPERIDONE
  • Safety Advice

    • Safety Warning

      Alcohol

      unsafe

      EPERISONE+PARACETAMOL and alcohol when taken together increase the chance of liver damage. Thus not recommended to be taken with alcohol.

    • Safety Warning

      Pregnancy

      caution

      There is no sufficient data to establish safe use of EPERISONE+PARACETAMOL in pregnant women. So, it should be used with caution.

    • Safety Warning

      Breast Feeding

      caution

      EPERISONE+PARACETAMOL may pass into breastmilk and cause unwanted effects in the nursing baby. So, it is not prescribed in breastfeeding mothers. However, if prescribed, the doctor may advise you to stop breastfeeding while using this medicine.

    • Safety Warning

      Driving

      caution

      EPERISONE+PARACETAMOL may cause dizziness, so do not drive or operate heavy machinery if you feel dizzy.

    • Safety Warning

      Liver

      caution

      EPERISONE+PARACETAMOL causes liver damage, so it should be used with caution in patients with liver diseases.

    • Safety Warning

      Kidney

      caution

      It should be used by kidney patients only if the doctor has prescribed it.

    • Safety Warning

      Children

      unsafe

      EPERISONE+PARACETAMOL is not recommended for use in children.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Exercising regularly helps in muscle stretching so that they are less likely to spasm, tear, and sprain. Mild exercises such as jogging and walking are helpful for muscle stretching.
    • Deep tissue massages with the help of a muscle massager are considered helpful.
    • Avoid wearing tight-fitting clothes, instead, wear loose garments.
    • Rest well and get optimal sleep (at least 8 hours for adults).
    • Hot or cold therapy can help treat muscle spasms.
    • Apply an ice pack or hot-pack on the muscle for 15-20 minutes.
    • Try to include glycine (protein) in your daily diet, which is good food for your muscle.

    Special Advise

    Your doctor may advise you to undergo regular blood tests to monitor liver function while using EPERISONE+PARACETAMOL.

    Patients Concern

    Disease/Condition Glossary

    Muscle spasm: The sudden involuntary contractions of the muscle can be painful and uncomfortable. When the nerve impulses that control the muscle movements are damaged or interrupted, it could lead to muscle spasms. Symptoms include muscle tightness, joint stiffness, unusual posture, difficulty moving, pain in affected muscles and joints. Fatigue (weakness), stress, extreme heat or cold, infection and tight clothing can trigger muscle spasms. Muscle relaxants and exercise can treat muscle spasms. Muscle relaxants sedate the muscle and help in inhibiting painful contractions. Exercise helps in muscle stretching so that they are less likely to spasm, tear and sprain.

    FAQs

    How does EPERISONE+PARACETAMOL work?

    EPERISONE+PARACETAMOL contains Eperinone and Paracetamol. Eperinone works by relaxing skeletal muscles and vascular smooth muscles (smooth muscle found in the wall of blood vessels). It can also suppress pain reflex. These effects of EPERISONE+PARACETAMOL help to reduce pain and spasms in the muscle effectively.

    Is EPERISONE+PARACETAMOL safe in diabetics?

    EPERISONE+PARACETAMOL may not affect blood glucose levels and is possibly safe when used in patients with diabetes. However, let your doctor know that you have diabetes before taking EPERISONE+PARACETAMOL.

    Are there any possible side-effects of EPERISONE+PARACETAMOL?

    The common side-effects of EPERISONE+PARACETAMOL are nausea, vomiting, stomach discomfort, headache, weakness, drowsiness, and dizziness. These side-effects are mild and temporary. However, inform your doctor immediately if any of these side-effects persist or get worse.

    Can I stop taking EPERISONE+PARACETAMOL if my symptoms are relieved?

    EPERISONE+PARACETAMOL is usually used for a short period and can be discontinued if there is no pain. However, it should be continued if advised by the doctor.

    Can I take EPERISONE+PARACETAMOL with oral contraceptives?

    Yes, it is absolutely safe to take both at a time as there are no reported interaction cases.

    Available Medicines for

    EPERISONE+PARACETAMOL