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Estriol

About Estriol

Estriol is used for hormone replacement therapy in menopausal women. It helps relieve menopausal symptoms like vaginal dryness, itching, and irritation occurring due to a shortage of estrogen in the body.  

Estriol contains ‘estriol’, which works by replacing the hormone, thereby helping relieve menopausal symptoms like vaginal dryness, itching, and irritation.

Estriol should be taken as advised by your doctor. The dose and duration of this medicine will be decided by the doctor based on your medical condition. In some cases, you may experience certain side effects such as headache, nausea, flu-like symptoms, breast discomfort and pain. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if the side effects persist or worsen.

Estriol is intended for use in post-menopausal women only; let your doctor know if you are pregnant or breastfeeding. Avoid alcohol consumption while on treatment with Estriol. Avoid taking this medicine if you are allergic to it.

Uses of Estriol

Treatment of Hormone Replacement Therapy (HRT)

Medicinal Benefits

Estriol belongs to a group of medicines called hormones indicated for hormone replacement therapy in menopausal women. It helps relieve menopausal symptoms like vaginal dryness, itching, and irritation occurring due to a shortage of estrogen in the body. Estriol contains ‘estriol’, which works by replacing the estrogen, thereby helping relieve menopausal symptoms like vaginal dryness, itching, and irritation.

Directions for Use

• Estriol can be taken with or without food. Taking it with food may help reduce stomach discomfort. • Take the medication once daily, or as prescribed by your doctor. • Swallow the medicine as a whole with a glass of water. • Do not chew, crush, or break it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Estriol

  • Headache
  • Nausea 
  • Flu-like symptoms
  • Breast discomfort and pain
  • Swelling of the ankles or feet
  • Vaginal irritation, bleeding, itching, and discharge

Drug Warnings

Do not take Estriol if you are allergic to it or if you have breast/womb/ovary cancer, unexplained/unusual vaginal bleeding, womb problems (thickening of the womb lining), blood clot disorders, recent stroke, liver disease, or porphyria (an inherited disorder that causes nerve or skin problems). Inform your doctor if you have endometriosis (abnormal growth of tissues outside the womb), womb tumours, high blood pressure, diabetes, gall bladder disease, migraine, epilepsy/fits/seizures, asthma, systemic lupus erythematosus (an autoimmune disease that causes inflammation), otosclerosis (hearing disorder due to growth of bone in the inner ear), or heart/kidney/liver problems. Let your doctor know if you are taking any prescription/non-prescription medicines or herbal/vitamin supplements.

Drug Interactions

Drug-Drug Interactions: Inform the doctor if you are taking anti-convulsant (phenytoin, carbamazepine), anti-viral (efavirenz, ritonavir, nelfinavir), anti-TB (rifampicin), herbal supplement to treat depression (St. John’s wort).

Drug-Food Interactions: No interactions found/established.

Drug-Disease Interactions: Inform the doctor if you have breast/womb/ovary cancer, unexplained/unusual vaginal bleeding, womb problems (thickening of the womb lining), blood clot disorders, recent stroke, liver disease, or porphyria (an inherited disorder that causes nerve or skin problems).

Drug-Drug Interactions Checker List:

  • PHENYTOIN
  • CARBAMAZEPINE
  • EFAVIRENZ
  • RITONAVIR
  • NELFINAVIR
  • RIFAMPICIN
  • ST JOHN'S WORT
  • Safety Advice

    • Safety Warning

      Alcohol

      unsafe

      Avoid consumption of alcohol while on treatment with Estriol.

    • Safety Warning

      Pregnancy

      caution

      Estriol is for use in post-menopausal women only. Consult your doctor if you are pregnant or planning pregnancy.

    • Safety Warning

      Breast Feeding

      caution

      Limited information is available. Consult your doctor if you are breastfeeding.

    • Safety Warning

      Driving

      consult your doctor

      It is not known if Estriol affects your ability to drive. Drive or operate machinery only if you are alert.

    • Safety Warning

      Liver

      caution

      Estriol is not recommended for use in patients with liver disease. Please consult your doctor if you have a liver impairment or any concerns regarding this.

    • Safety Warning

      Kidney

      consult your doctor

      Please consult your doctor if you have kidney impairment or any concerns regarding this.

    • Safety Warning

      Children

      consult your doctor

      Limited information is available. Please consult your doctor if you have any concerns.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Include foods such as soybeans, flax seeds, and soy products in the diet.

    • Maintain a healthy weight by exercising regularly. Also, avoid exercising too much. Do it moderately.

    • Drink plenty of water to stay hydrated.

    • Try to limit alcohol and caffeine.

    Special Advise

     

    Patients Concern

    Disease/Condition Glossary

    Hormone Replacement Therapy (HRT): It is a treatment that replaces/boost hormones that are at a low level and helps relieve symptoms of menopause such as night sweats, hot flushes, vaginal dryness, mood swings, and reduced sex drive.

    FAQs

    Estriol is indicated for hormone replacement therapy in menopausal women. It helps relieve menopausal symptoms like vaginal dryness, itching, and irritation occurring due to a shortage of estrogen in the body.Â

    If you miss a dose, take the missed dose as soon as you remember. If it is almost time for the scheduled dose, skip the missed dose and take the scheduled dose instead. Avoid doubling the dose.

    Estriol might cause vaginal irritation, bleeding, itching, and discharge. Consult your doctor if you notice unexplained/unusual/abnormal vaginal bleeding.

    Take Estriol as advised by your doctor. But try to take it at the same time every day, to maintain consistent levels of Estriol in your body.

    The common side effects of Estriol include headache, nausea, flu-like symptoms, swelling of feet or ankles, breast discomfort and pain and vaginal irritation, bleeding, discharge or itching. If these side effects persist or worsen, please consult your doctor.

    Available Medicines for

    Estriol

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