Don't stop taking HYDROCHLOROTHIAZIDE+METOPROLOL without talking to your doctor first. Stopping HYDROCHLOROTHIAZIDE+METOPROLOL gradually may cause changes in your heart rhythm and blood pressure, cause chest pain, or a heart attack. Your doctor will lower your dose gradually over a period of time to help prevent these symptoms. You should not use HYDROCHLOROTHIAZIDE+METOPROLOL if you have allergic to HYDROCHLOROTHIAZIDE+METOPROLOL, have low blood pressure (less than 90 mm of Hg), very slow heartbeat, serious lung condition (like asthma), serious heart condition (sick sinus syndrome), or any heart blockage. Do not use HYDROCHLOROTHIAZIDE+METOPROLOL if you are pregnant, planning for pregnancy, breastfeeding, or unable to urinate (anuria). It should not be given to the children as safety and effectiveness have not been established. Before taking HYDROCHLOROTHIAZIDE+METOPROLOL you should tell the doctor if you have any muscle disorder (myasthenia gravis, rhabdomyolysis), breathing problem (COPD, bronchitis, emphysema), low blood sugar level (hypoglycemia), eye problem (glaucoma), low blood pressure (hypotension), depression, previous heart failure, liver/kidney disease, thyroid hormone disorder like overactive thyroid (hyperthyroidism), adrenal gland cancer, or severe blood circulation problem (Raynaud’s syndrome). You should monitor your blood pressure regularly to make sure the HYDROCHLOROTHIAZIDE+METOPROLOL is working efficiently. Besides this, prolonged intake of HYDROCHLOROTHIAZIDE+METOPROLOL can lead to lowering of blood pressure (hypotension). So, daily monitoring of blood pressure is advisable.

Drug-Drug Interactions: HYDROCHLOROTHIAZIDE+METOPROLOL may interact with other blood pressure-lowering pills or beta-blockers (acebutolol, atenolol, bisoprolol, carteolol, esmolol, nadolol,) other blood pressure-related medicines (lisinopril, enalapril, diltiazem, prazosin, terazosin, ramipril, atorvastatin), diuretics (furosemide, chlorothiazide, chlorthalidone, indapamide, metolazone), asthma medications (theophylline, aminophylline), pain killers (ibuprofen, aspirin), antifungals (terbinafine), anticancer (aldesleukin), blood thinner (dipyridamole), antibiotics (rifampicin), antivirals (ritonavir), antihistamines used to treat hay fever (diphenhydramine), medicines used to treat irregular heartbeat (amiodarone, propafenone, quinidine, disopyramide, procainamide, digoxin, lidocaine), anti-epilepsy medications (carbamazepine, phenobarbital), immune-suppressing drugs (cyclosporine).

Drug-Food Interactions: HYDROCHLOROTHIAZIDE+METOPROLOL severely interacts with grapefruit and protein-enriched foods. Using HYDROCHLOROTHIAZIDE+METOPROLOL with ayurvedic, homoeopathy, Unani, herbal supplements, or other OTC items may decrease the effects of HYDROCHLOROTHIAZIDE+METOPROLOL. Hence, it is better to maintain at least 2 hours gap between the administration of HYDROCHLOROTHIAZIDE+METOPROLOL and these products.

Drug-Disease Interactions: HYDROCHLOROTHIAZIDE+METOPROLOL should not be given to people with diabetes, thyroid disease, asthma, cardiogenic shock (when the heart fails to pump required blood to the body), heart valve problem (stenosis), low blood pressure (hypotension), coronary heart disease, liver disease or heart failure, gout, low serum potassium (hypokalemia), patients with nil urine output (anuria).

• Consume antioxidant-rich food. Blueberries, cherries, tomatoes, squash, and bell peppers are high in antioxidants.
• Eat natural diuretic foods. Asparagus, beets, green beans, grapes, onion, leafy greens, pineapple, leeks, pumpkin, and garlic are all-natural diuretic foods.
• Use healthy cooking oils like soybean, olive, canola, and coconut oil.
• You should avoid refined foods such as white bread, spaghetti, sugar, and red meat.
• Reduce or eliminate Trans fatty acids, which are found in commercially baked items such as cookies, cakes, crackers, French fries, onion rings, doughnuts, and processed foods.
• Avoid the consumption of too much salt or salty food.
• Keep your weight under control with a BMI of 19.5-24.9.
• Regular physical activity or exercise like walking improves your blood flow.
• When possible, elevate your legs or the swollen area on a chair or pillows.
• Avoid standing or sitting for extended periods of time.
• Avoid chronic stress as it can raise your blood pressure.
• Spend time with your loved ones to cope with stress and practice mindfulness techniques.
• Quitting smoking and alcohol consumption is the best strategy to lower the risk of many health complications.