Itopride Hydrochloride
About Itopride Hydrochloride
Itopride Hydrochloride is used in the treatment of disorders associated with reduced gastrointestinal motility. Besides this, Itopride Hydrochloride also treats gastrointestinal disorders like dyspepsia (indigestion), bloating (feeling of stomach tightness due to gas), upper abdominal pain, anorexia (eating disorder), heartburn, nausea and vomiting.
Itopride Hydrochloride contains Itopride hydrochloride, which works by increasing the level of acetylcholine concentration, which in turn increases the gastrointestinal peristalsis movement, thereby accelerating gastric emptying time and easing the movement of food through the entire gastrointestinal tract.
In some cases, you may experience diarrhoea, stomach pain, headache, dry mouth or drowsiness. Most of these side effects of Itopride Hydrochloride do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
If you are known to be allergic to Itopride Hydrochloride or any other medicines, please tell your doctor. Itopride Hydrochloride is not recommended for children below 16 years of age. If you are pregnant or breastfeeding, please inform your doctor before taking Itopride Hydrochloride. If you have Parkinson's disease or internal bleeding of the stomach and intestine, please consult a doctor before taking Itopride Hydrochloride.
Uses of Itopride Hydrochloride
• Treatment of Functional Dyspepsia: Itopride Hydrochloride is frequently used to alleviate functional dyspepsia symptoms such as pain, bloating, and nausea.
• Management of Gastroesophageal Reflux Disease: Itopride Hydrochloride aids in the treatment of GERD, such as heartburn and acid ingestion, by increasing stomach motility and decreasing the frequency of reflux events.
• Relief from Nausea and Vomiting: Itopride Hydrochloride significantly reduces nausea and vomiting caused by gastroenteritis and chemotherapy, thereby regulating digestive function.
• Postoperative Gastric Motility Disorders: Itopride Hydrochloride can also be used to treat patients who have delayed gastric emptying following surgery.
• Gastroparesis Management: Itopride Hydrochloride can be prescribed to treat gastroparesis by improving gastric motility in patients with weak stomach muscles.
Medicinal Benefits
- Itopride Hydrochloride is a gastroprokinetic (enhances the movement of food from the mouth through the stomach and intestines).
- In normal digestion conditions, the food is moved through the entire digestive tract (food pipe, stomach, small intestine, and large intestine) by a rhythmic contraction, i.e., peristalsis movement. This regular movement of the digestive tract is called 'gastric motility.'
- When an individual suffers from a digestive motility problem, these digestive tract contractions do not work correctly, leading to various gastrointestinal issues.
- Itopride Hydrochloride is used for treating gastrointestinal symptoms such as heartburn, vomiting, nausea, bloating, indigestion, and discomfort or pain in the stomach.
- Itopride Hydrochloride prevents heartburn by enhancing the movement of food through the stomach and intestines.
- Also, Itopride Hydrochloride acts on the chemoreceptor trigger zone (the area that triggers vomiting) in the brain and prevents vomiting.
Directions for Use
- Itopride Hydrochloride is taken before meals or as advised by your doctor.
- It is usually taken three times in a day or as prescribed by the doctor.
- Swallow it as a whole with a glass of water.
- Do not chew, crush or break it.
Storage
Side Effects of Itopride Hydrochloride
- Diarrhoea
- Stomach pain
- Headache
- Dry mouth
- Drowsiness
- Constipation
- Dizziness
Drug Warnings
- Avoid taking Itopride Hydrochloride if you are allergic to it or any other components present in it.
- Patients with reduced kidney or liver function should be monitored carefully, and the dose should be adjusted accordingly.
- Itopride Hydrochloride may be excreted in breast milk. Therefore, breastfeeding or pregnant women are advised to consult a doctor before taking Itopride Hydrochloride.
- If you notice dark, coffee coloured stools or blood in stools, contact your doctor immediately, as these might be signs of bleeding in the stomach.
- Do not take Itopride Hydrochloride if you have increased gastrointestinal haemorrhage (internal bleeding of the intestine and stomach), gastrointestinal motility (movement of food from the mouth through the stomach and intestine), or mechanical perforation or obstruction, as it may worsen the condition.
Drug Interactions
Drug-Drug Interactions: Itopride Hydrochloride may interact with anticholinergic agents (dicyclomine, trihexyphenidyl, ipratropium, belladonna alkaloids, benztropine mesylate, flavoxate, atropine, scopolamine and hyoscyamine).
Drug-Food Interactions: Itopride Hydrochloride may interact with grapefruit juice. Therefore, avoid consuming grapefruit juice with Itopride Hydrochloride as it may increase the risk of adverse effects.
Drug-Disease Interactions: Do not use Itopride Hydrochloride in patients with Parkinson’s disease, gastrointestinal bleeding, Lapp lactase deficiency, galactose intolerance or glucose-galactose malabsorption.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
consult your doctorThe interaction of alcohol with Itopride Hydrochloride is unknown. Please consult a doctor before consuming alcohol while using Itopride Hydrochloride.
Pregnancy
consult your doctorLet your doctor know if you are a nursing mother before taking Itopride Hydrochloride; your doctor will decide whether Itopride Hydrochloride can be taken by breastfeeding mothers or not.
Breast Feeding
consult your doctorLet your doctor know if you are a nursing mother before taking Itopride Hydrochloride; your doctor will decide whether Itopride Hydrochloride can be taken by breastfeeding mothers or not.
Driving
cautionItopride Hydrochloride may cause dizziness or reduce alertness in some people. So, drive only if you are alert after taking Itopride Hydrochloride.
Liver
cautionTake Itopride Hydrochloride with caution, especially if you have a history of liver disease. The dose may be adjusted by your doctor as required.
Kidney
cautionTake Itopride Hydrochloride with caution, especially if you have a history of kidney disease. The dose may be adjusted by your doctor as required.
Children
unsafeItopride Hydrochloride is not recommended for children below 16 years as the safety and effectiveness were not established.
Habit Forming
Diet & Lifestyle Advise
- Avoid certain foods such as tomatoes, coffee, chocolate, and spicy and fatty foods as they may cause heartburn or worsen the condition.
- Eat small portions of food frequently.
- Do regular exercise, such as for a minimum of 30 minutes daily. Maintain a healthy body weight, as obesity may also cause heartburn.
- Avoid consumption of alcohol and quit smoking.
- Avoid fast food, fried food, processed meats, refined carbs and added sugars.
Special Advise
- If you are suffering from rare hereditary Lapp lactase deficiency problems, galactose intolerance or glucose-galactose malabsorption, avoid taking Itopride Hydrochloride as it contains lactose.
Patients Concern
Disease/Condition Glossary
Gastric motility disorder: In the normal digestion condition, the food is moved through the entire digestive tract (food pipe, stomach, small intestine and large intestine) by a rhythmic contraction, i.e. peristalsis movement. This regular movement of the digestive tract is called 'gastric motility.' When an individual suffers from a digestive motility problem, these digestive tract contractions do not work properly, leading to various gastrointestinal issues.
FAQs
Itopride Hydrochloride is used to treat dyspepsia (indigestion), bloating (feeling of stomach tightness due to gas), upper abdominal pain, anorexia (eating disorder), heartburn, nausea and vomiting.
Itopride Hydrochloride contains Itopride, which works by increasing the level of acetylcholine concentration, which in turn increases the gastrointestinal peristalsis movement thereby, accelerating gastric emptying time and eases the movement of food through the entire gastrointestinal tract. Itopride Hydrochloride also stops the sensation of vomiting/nausea by blocking the D2 receptors located in the chemoreceptor trigger zone - CTZ of the brain responsible for inducing vomiting.
Yes, Itopride Hydrochloride may cause diarrhoea as a common side effect. However, if the condition persists, worsens with fever, watery stools or consistent stomach pain, please consult a doctor. Also, drink plenty of water while taking Itopride Hydrochloride to prevent dehydration.
Yes, Itopride Hydrochloride may cause gynecomastia (enlargement of breast tissue in males) in some people. It is not necessary for everyone taking Itopride Hydrochloride to experience this side effect. However, if you notice any signs of breast swelling, please consult a doctor immediately.
No, Itopride Hydrochloride is not recommended for patients with gastrointestinal haemorrhage (internal bleeding of intestine and stomach) as it may lead to gastrointestinal perforation (ruptured bowel).
No, you are not recommended to take Itopride Hydrochloride with dicyclomine as co-administration of these two medicines may reduce the effect of Itopride Hydrochloride. However, please consult your doctor before taking Itopride Hydrochloride with other medicines.
Itopride Hydrochloride should be swallowed as a whole with water; do not crush or chew it.
Itopride Hydrochloride is not recommended for children below 16 years as the safety and effectiveness were not established.
Itopride Hydrochloride should be used during pregnancy only if prescribed by the doctor. Consult the doctor if you are pregnant, think you may be pregnant or are planning to have a baby.
Itopride Hydrochloride should be taken for as long as it has been prescribed by the doctor. The doctor will determine the duration of the treatment based on your condition.
Itopride hydrochloride is eliminated primarily by the kidneys. Patients with reduced kidney function should be monitored carefully, and the dose should be adjusted accordingly. If you have any kidney-related diseases, please consult the doctor before taking Itopride Hydrochloride.
Do not take Itopride Hydrochloride if you are allergic to any of its components or if you suffer from gastrointestinal bleeding, obstruction or perforation.
Itopride Hydrochloride should be taken before meals or as advised by the doctor.
Itopride Hydrochloride is a gastroprokinetic agent (enhances the movement of food from the mouth through the stomach and intestines) that is used for treating gastrointestinal symptoms.
Itopride Hydrochloride may cause side effects like diarrhoea, stomach pain, headache, tremor (involuntary movement) and drowsiness. Most of these side effects of Itopride Hydrochloride do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
Consult the doctor before taking Itopride Hydrochloride if you have pre-existing medical conditions such as Parkinson's disease or internal bleeding of the stomach and intestine.
Before starting Itopride Hydrochloride, let your doctor know if you are a nursing mother; your doctor will decide whether Itopride Hydrochloride can be taken by breastfeeding mothers or not.
