Lamivudine+zidovudine+nevirapine
About Lamivudine+zidovudine+nevirapine
Lamivudine+nevirapine+zidovudine belongs to a class of medications called antiretrovirals, primarily used to treat HIV (human immunodeficiency virus) infection. HIV is a virus that attacks the body's immune system. If HIV is not treated, it can lead to AIDS (acquired immunodeficiency syndrome), making an individual more susceptible to other infections and diseases like cancer.
Lamivudine+nevirapine+zidovudine is a combination of three medications: lamivudine, zidovudine, and nevirapine. Lamivudine and zidovudine are nucleosidase reverse transcriptase inhibitors that work together to decrease the amount of virus in your body by inhibiting HIV reverse transcription through viral DNA chain termination. Nevirapine is a non-nucleosidase reverse transcriptase inhibitor that works by lowering the amount of HIV in the blood. Lamivudine+nevirapine+zidovudine will not cure HIV infection or AIDS; however, it helps keep HIV from reproducing and appears to slow down the destruction of the immune system.
You should take Lamivudine+nevirapine+zidovudine at the dose and duration prescribed by your doctor. You may experience common side effects of Lamivudine+nevirapine+zidovudine, such as nausea, vomiting, diarrhoea, headache, heartburn, depression, cough, stuffy nose, joint pain, and insomnia (difficulty falling asleep). Most of the side effects of Lamivudine+nevirapine+zidovudine do not require medical attention and typically resolve on their own over time. However, if the side effects persist, contact your doctor.
Before taking Lamivudine+nevirapine+zidovudine, inform your doctor if you are allergic to any of its ingredients. Always keep your doctor informed about any medications you are currently taking to avoid potential side effects or interactions. Let your doctor know if you have severe liver or kidney disease, severe skin reactions, blood-related problems, myopathy (muscle weakness), and lactic acidosis (buildup of lactic acid in the blood). Consult your doctor before taking Lamivudine+nevirapine+zidovudine if you are pregnant or planning to become pregnant. Avoid breastfeeding while taking Lamivudine+nevirapine+zidovudine, as it may pass into breast milk. Lamivudine+nevirapine+zidovudine may cause dizziness or sleepiness, so avoid driving or operating machines until you know how it affects you.
Uses of Lamivudine+zidovudine+nevirapine
• Treatment of HIV infection: Lamivudine+nevirapine+zidovudine helps decrease the amount of virus in the body and delay the progression of HIV infection to AIDS.
• Improves Immune Function: Lamivudine+nevirapine+zidovudine helps increase the number of immune cells (CD4+ T cells), thereby improving the immune system.
• Prevention of Mother-to-Child Transmission of HIV: Lamivudine+nevirapine+zidovudine may be prescribed in pregnant women with HIV to reduce the risk of transmitting the virus to the baby during pregnancy.
Medicinal Benefits
Lamivudine+nevirapine+zidovudine belongs to a class of medications called antiretrovirals, primarily used to treat HIV (human immunodeficiency virus) infection. It contains lamivudine, zidovudine, and nevirapine. Lamivudine+nevirapine+zidovudine work by preventing HIV (virus) from multiplying, thereby reducing the amount of virus in your body. They also increase the CD4+ cell (white blood cells that protect against infection) count in your blood. Lamivudine+nevirapine+zidovudine will not cure HIV infection or AIDS; however, it helps keep HIV from reproducing and appears to slow down the destruction of the immune system. Lamivudine+nevirapine+zidovudine also helps to reduce the risk of transmitting the virus to the baby during pregnancy.
Directions for Use
- Take Lamivudine+nevirapine+zidovudine with or without food, or as advised by a doctor.
- Follow your doctor's instructions on the dosage and timing of this medication.
- Swallow the medicine as a whole with a glass of water.
- Do not crush, break, or chew it.
Storage
Side Effects of Lamivudine+zidovudine+nevirapine
- Nausea
- Vomiting
- Diarrhoea
- Headache
- Heartburn
- Depression
- Cough
- Stuffy nose
- Joint pain
- Insomnia (difficulty falling asleep)
Drug Warnings
Do not take Lamivudine+nevirapine+zidovudine if you are allergic to any one of its components. Always keep your doctor informed about any medications you are currently taking, including over-the-counter medicines, vitamins, or herbal supplements, to avoid potential side effects or interactions. Inform your doctor before taking Lamivudine+nevirapine+zidovudine if you have any medical conditions, such as severe liver or kidney disease, severe hepatomegaly (enlarged liver), severe skin reactions, blood-related problems, myopathy (muscle weakness), lactic acidosis (buildup of lactic acid in the blood), and worsening of hepatitis B infection. Lamivudine+nevirapine+zidovudine may cause birth defects; therefore, use effective contraception while taking Lamivudine+nevirapine+zidovudine and for 12 weeks after stopping it. Consult your doctor before taking Lamivudine+nevirapine+zidovudine if you are pregnant or planning to become pregnant. Avoid breastfeeding if you are infected with HIV or while taking Lamivudine+nevirapine+zidovudine, as it may pass into breast milk and harm the baby. Lamivudine+nevirapine+zidovudine may cause dizziness or sleepiness, so avoid driving or performing any activities that require concentration until you know how it affects you.
Drug Interactions
Drug-Drug Interaction: Lamivudine+nevirapine+zidovudine may interact with antibiotics (clarithromycin, chloramphenicol, doxorubicin), antivirals (acyclovir, atazanavir, efavirenz), and antifungals (fluconazole, ketoconazole).
Drug-Food Interaction: Avoid taking alcohol and St. John's wort with Lamivudine+nevirapine+zidovudine.
Drug-Disease Interaction: Inform your doctor before taking Lamivudine+nevirapine+zidovudine if you have any medical conditions, such as severe liver or kidney disease, severe hepatomegaly (enlarged liver), severe skin reactions, blood-related problems, myopathy (muscle weakness), lactic acidosis (buildup of lactic acid in the blood), and worsening of hepatitis B infection.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
unsafeTaking Lamivudine+nevirapine+zidovudine with alcohol may increase the risk of liver damage. So, avoid alcohol consumption while taking Lamivudine+nevirapine+zidovudine.
Pregnancy
safeLamivudine+nevirapine+zidovudine can be used during pregnancy under the supervision of a doctor. Studies have not shown any defects in the unborn baby, even though Lamivudine+nevirapine+zidovudine passes through the placenta. Lamivudine+nevirapine+zidovudine helps reduce the risk of transmitting the virus to the baby during pregnancy.
Breast Feeding
unsafeAvoid breastfeeding if you are infected with HIV or while taking Lamivudine+nevirapine+zidovudine.
Driving
unsafeLamivudine+nevirapine+zidovudine may cause dizziness or sleepiness. Do not drive or do anything requiring concentration until you know how it affects you.
Liver
cautionInform your doctor before taking Lamivudine+nevirapine+zidovudine if you have severe liver disease. Your doctor may advise you not to take Lamivudine+nevirapine+zidovudine. Inform your doctor immediately if you develop symptoms such as abdominal pain, loss of appetite, dizziness, bruising, irregular heartbeats, yellowing of the eyes or skin, or darkened urine.
Kidney
cautionInform your doctor before taking Lamivudine+nevirapine+zidovudine if you have severe kidney disease. Your doctor may need to adjust the dose of Lamivudine+nevirapine+zidovudine.
Children
unsafeLamivudine+nevirapine+zidovudine should not be used in children weighing less than 35 kg. If their weight is >35, your doctor may prescribe Lamivudine+nevirapine+zidovudine and adjust the dose.
Habit Forming
Diet & Lifestyle Advise
- Eat a balanced diet – Include fruits, vegetables, whole grains, lean proteins, and healthy fats to support your immune system.
- Stay well-hydrated – Drink plenty of safe, clean water to help with digestion and medication absorption.
- Avoid raw or undercooked foods – Reduce the risk of foodborne infections by eating properly cooked meals.
- Limit sugar and processed foods – These can weaken the immune system and cause weight or blood sugar issues.
- Maintain a healthy weight – Aim for a weight that supports overall health and energy without stressing your body.
- Exercise regularly – Engage in moderate activity like walking or yoga to boost energy and mood.
- Take medications as prescribed – Follow your treatment plan strictly, and take medicines with food if recommended.
- Avoid smoking and alcohol – These can interfere with treatment and weaken your immune system.
- Practice good hygiene – Wash hands often and handle food safely to prevent infections.
- Attend regular medical checkups – Keep in touch with your doctor and report any side effects or concerns promptly.
Patients Concern
Disease/Condition Glossary
HIV (human immunodeficiency virus): HIV is a virus that attacks the body’s immune system. If HIV is not treated, it can lead to AIDS (acquired immunodeficiency syndrome). There is currently no effective cure. Once people get HIV, they have it for life. But with proper medical care, HIV can be controlled. People with HIV who get effective treatment can live long, healthy lives and protect their partners. Some people have flu-like symptoms within 2 to 4 weeks after infection (called acute HIV infection). These symptoms may last for a few days or several weeks. Possible symptoms include fever, chills, rash, muscle aches, night sweats, fatigue, sore throat, mouth ulcers, and swollen lymph nodes.
FAQs
Lamivudine+nevirapine+zidovudine belongs to a class of medications called antiretrovirals, primarily used to treat HIV (human immunodeficiency virus) infection. It also helps delay the progression of HIV infection to AIDS and reduces the risk of transmitting the virus to the baby during pregnancy.
If you miss a dose of Lamivudine+nevirapine+zidovudine, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.
Yes, Lamivudine+nevirapine+zidovudine causes the weakening of bones. Exercise regularly and take calcium and vitamin D supplements as suggested by your doctor.
Lamivudine+nevirapine+zidovudine is a combination of three medications: lamivudine, zidovudine, and nevirapine. Lamivudine and zidovudine are nucleosidase reverse transcriptase inhibitors that work together to decrease the amount of virus in your body by inhibiting HIV reverse transcription through viral DNA chain termination. Nevirapine is a non-nucleosidase reverse transcriptase inhibitor that works by lowering the amount of HIV in the blood. Lamivudine+nevirapine+zidovudine will not cure HIV infection or AIDS; however, it helps keep HIV from reproducing and appears to slow down the destruction of the immune system.
The common side effects of Lamivudine+nevirapine+zidovudine include nausea, vomiting, diarrhoea, headache, heartburn, depression, cough, stuffy nose, joint pain, and insomnia (difficulty falling asleep). Most of the side effects of Lamivudine+nevirapine+zidovudine do not require medical attention and typically resolve on their own over time. However, if the side effects persist, contact your doctor.
HIV is a virus that attacks the body’s immune system. If HIV is not treated, it can lead to AIDS (acquired immunodeficiency syndrome). There is currently no effective cure. But with proper medical care, HIV can be controlled. Some people have flu-like symptoms within 2 to 4 weeks after infection (called acute HIV infection). These symptoms may last for a few days or several weeks. Possible symptoms include fever, chills, rash, muscle aches, night sweats, fatigue, sore throat, mouth ulcers, and swollen lymph nodes.
