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About PAPAIN+UREA

PAPAIN+UREA belongs to the class of medications called 'Debridement agents' used to remove dead skin, thereby improving healing. It also helps thin the pus in lesions (ulcers, cysts, bedsores, surgical wounds).

PAPAIN+UREA contains Papain and Urea. These two medicines are keratolytic agents, increase moisture in the skin, and dissolve the keratin (protein present on the skin's outer layer). This effect makes dead skin cells fall off and accelerate healing. It also has an emollient effect and helps to soften the skin.

You should use this medicine exactly as prescribed by the doctor. The common side effects of PAPAIN+UREA are a burning sensation, itching, and irritation in the treated area. These side effects are usually mild and temporary. However, if these side effects persist or worsen, inform your doctor immediately.

It is not recommended to take PAPAIN+UREA if you are allergic to any contents of it. Before taking PAPAIN+UREA, inform your doctor if you have liver or kidney disease and poor blood circulation. Do not use this medication on skin cuts, infections, or sores. PAPAIN+UREA should be used with caution in pregnant women, breastfeeding mothers, and older people. It is not recommended for use in children less than two years. PAPAIN+UREA may not interact with alcohol and may not affect your driving ability.

Uses of PAPAIN+UREA

Dead skin removal, Wound healing.

Medicinal Benefits

PAPAIN+UREA belongs to the class of medications called 'Debridement agents' used to remove dead skin and promote wound healing. PAPAIN+UREA contains Papain and Urea, which help remove dead skin from wounds and speed up recovery. It also helps thin the pus in lesions (ulcers, cysts, bedsores, surgical wounds). These two medicines increase moisture in the skin and dissolve keratin (a protein on the skin's outer layer). This effect makes dead skin cells fall off and accelerate healing. It also has an emollient effect and helps to soften the skin.

Directions for Use

Gently rinse the affected area with saline or water before applying PAPAIN+UREA. Pat the skin and dry it with a clean cotton towel. Apply a generous amount of PAPAIN+UREA and spread it evenly on the affected areas of the skin to form a 1/8-inch thick layer with clean and dry hands. You can also apply PAPAIN+UREA with a piece of clean cotton wool or gauze swab. Wash your hands before and after using PAPAIN+UREA on the affected areas unless the treatment is for hands.

Storage

Store in a cool and dry place away from sunlight

Side Effects of PAPAIN+UREA

  • Burning sensation
  • Itching of treated skin
  • Skin irritation

In-Depth Precautions and Warning

Drug Warnings

PAPAIN+UREA is for topical (skin) use only. Do not use the medicine in and around your eyes. If the medicine accidentally gets into your eyes, nose, mouth, or genitals, rinse it with water thoroughly. It should not be given to children with a fever, especially if they have flu symptoms or chickenpox. PAPAIN+UREA may increase skin sensitivity to the sun, so take necessary precautions while going outside and avoid tanning beds or sunlamps. If you notice any persistent skin irritation or worsening of the skin disease, stop using PAPAIN+UREA and immediately inform your doctor.

Drug Interactions

Drug-Drug Interactions: PAPAIN+UREA is known to interact with other topical medicines containing hydrogen peroxide, silver nitrate, silver sulfadiazine, silver, mercury, lead, and thimerosal.

Drug-Food Interactions: No interactions found.

Drug-Disease Interactions: PAPAIN+UREA should be used with caution in patients with liver or kidney diseases and poor blood circulation.

 

Drug-Drug Interactions Checker List:

  • HYDROGEN PEROXIDE
  • SILVER NITRATE
  • SILVER
  • SILVER SULFADIAZINE
  • THIMEROSAL
  • Safety Advice

    • Safety Warning

      Alcohol

      safe if prescribed

      PAPAIN+UREA may not interact with alcohol.

    • Safety Warning

      Pregnancy

      caution

      PAPAIN+UREA contains urea, a Category C pregnancy drug that may cause harmful effects on the unborn baby. So, it is given to a pregnant woman only if the doctor thinks the benefits outweigh the risks.

    • Safety Warning

      Breast Feeding

      caution

      It is not known whether PAPAIN+UREA can pass into breast milk. So, it is given to a breastfeeding mother only if the doctor thinks the benefits outweigh the risks.

    • Safety Warning

      Driving

      safe if prescribed

      PAPAIN+UREA may not affect your ability to drive.

    • Safety Warning

      Liver

      caution

      PAPAIN+UREA should be used with caution in patients with liver diseases. The dose may have to be adjusted by your doctor.

    • Safety Warning

      Kidney

      caution

      PAPAIN+UREA should be used with caution in patients with kidney diseases. The dose may have to be adjusted by your doctor.

    • Safety Warning

      Children

      caution

      PAPAIN+UREA is not recommended for children below two years. In children above two years, it is given only if the doctor thinks the benefits outweigh the risks.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Use mild soap while taking baths and prefer warm baths.
    • Avoid harsh products on your skin.
    • Do not scratch or pick your skin to avoid infecting the affected area.
    • Manage stress, eat healthily, drink plenty of water, exercise regularly, and get plenty of sleep.
    • Limit food intake that might trigger allergies, such as dairy products, soy, eggs, and nuts.
    • Avoid consuming foods with excess sugar, as it may flare up inflammation.
    • Include fruits, vegetables, whole grains, healthy fats, and fish.
    • Avoid getting in contact with harsh soaps, detergents, and rough fabrics.
    • Wear clothes with long sleeves, a hat, and sunscreen with high SPF while outdoors.
    • Avoid tanning booths and sunlamps.

    Special Advise

    • Before applying PAPAIN+UREA, avoid using hydrogen peroxide to clean your wound, as it might affect the effectiveness of PAPAIN+UREA.
    • If there is no improvement in your condition after 4-6 weeks of treatment with PAPAIN+UREA, consult your dermatologist.

    Patients Concern

    Disease/Condition Glossary

    Debridement: It is a procedure for treating wounded skin. These agents help to remove dead skin and tissues from wounds, including ulcers, cysts, bedsores, and surgical wounds. Sometimes, it is also used to remove foreign material from tissues. It also helps to speed up the healing process of wounds.

    FAQs

    How does PAPAIN+UREA work?

    PAPAIN+UREA contains Papain and Urea. These two medicines are keratolytic agents (soften, separate, and peel off the horny layer of skin). They dissolve the keratin (protein present on the outer layer of skin), remove dead skin cells, and soften the skin.

    Are there any possible side-effects of PAPAIN+UREA?

    The common side effects of PAPAIN+UREA are a burning sensation, itching, and irritation in the treated area. These side effects are usually mild and temporary. However, if any of these side effects persist or worsen, inform your doctor immediately.

    Can I use other skin creams while using PAPAIN+UREA?

    It is advised to avoid using other topical medicines on the affected area while using PAPAIN+UREA. So, inform your doctor before using any medications while using the PAPAIN+UREA. If the doctor prescribes other skin creams or ointments along with PAPAIN+UREA, you should maintain an interval of at least 30 min between the two medications.

    Can PAPAIN+UREA be used to treat diaper rash?

    PAPAIN+UREA should not be used to treat diaper rash or redness. It is not recommended for use in children below 2 years of age.

    What precautions should I take while using PAPAIN+UREA?

    PAPAIN+UREA is for topical use (for skin) only. Do not use the PAPAIN+UREA on the skin that is red, swollen, oozing, and infected, and avoid contact with eyes, nose, mouth, and genitals. It can make your skin more sensitive to the harmful effects of sunlight. So, using sunscreen and wearing protective clothing while using PAPAIN+UREA is advised. It is recommended to avoid tanning booths and sunlamps. Please do not use it on larger areas and for prolonged periods unless prescribed by the doctor.

    Available Medicines for

    PAPAIN+UREA