1. Different Drug Classes: Monocef (Cefpodoxime) is an antibiotic, while Diamox (Acetazolamide) is a diuretic. Allergies to one do not typically imply allergies to the other.

2. Allergy History: If you have multiple drug allergies or severe reactions, exercise caution.

3. Consult Your Doctor: Discuss your allergy history with your healthcare provider before taking Diamox.

4. Monitoring: If prescribed, watch for allergic reactions like rash, itching, or difficulty breathing.

In summary, being allergic to Monocef doesn't automatically mean you can't take Diamox, but consult your doctor first.