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  5. I have a history of depression, and I frequently experience heartburn, indigestion, acid reflux, oesophageal inflammation, difficulty swallowing, stomach or intestinal ulcers, and irritable bowel syndrome (IBS). Can depression contribute to or worsen these gastrointestinal symptoms?

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I have a history of depression, and I frequently experience heartburn, indigestion, acid reflux, oesophageal inflammation, difficulty swallowing, stomach or intestinal ulcers, and irritable bowel syndrome (IBS). Can depression contribute to or worsen these gastrointestinal symptoms?

Asked by Male, 40 · 2 months ago

Dr S Aneela

Dr S Aneela

M. Pharm (Pharmacology)., PhD

2 months ago

Yes, depression can contribute to and worsen these gastrointestinal symptoms. Stress and mood disturbances affect the brain?gut connection, which can increase stomach acid production and alter bowel movements, leading to problems such as gastroesophageal reflux disease (GERD), esophagitis, peptic ulcers, and IBS. Depression can also heighten pain perception and delay healing of the digestive lining, so managing both the mood disorder and the gastrointestinal symptoms together is often more effective than treating either condition alone.
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  1. Connection Between Depression and Gastrointestinal Symptoms

    • Depression can influence gastrointestinal symptoms through the brain-gut axis, potentially worsening conditions like heartburn, acid reflux, and IBS.

  2. Impact on Specific Gastrointestinal Conditions

    • Depression may exacerbate oesophageal inflammation, difficulty swallowing, and ulcers by increasing stress and inflammation.

  3. Role of Stress and Neurotransmitters

    • Stress hormones and neurotransmitter imbalances in depression can alter gut motility and sensitivity, affecting digestion.

  4. Importance of Integrated Care

    • Addressing both mental health and gastrointestinal symptoms together is crucial for effective management.

  5. When to Seek Medical Advice

    • Consult healthcare providers for tailored treatment, including medications, lifestyle changes, and therapy.

  6. Relevant Medical Specialties and Treatments

    • Consider consulting gastroenterologists and mental health professionals. Antidepressants may help manage both conditions.

Answered 2 months ago

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