What are the potential causes of a persistent, 8-month-long burning sensation in a 50-year-old female with diabetes, hypertension, and a 14 mm kidney stone, whose symptoms have not responded to anti-reflux treatment (Panplus D, Rebagem) and who is currently taking a complex medication regimen including Metformin, Glimepiride, Clopidogrel, Nicorandil, Olmesartan, and Pregabalin/Amitriptyline?
Because your symptoms didn't improve with anti-reflux medicines like pantoprazole/domperidone (Panplus D) or rebamipide (Rebagem), the burning might not be standard reflux. It could be a side effect of other medications you are taking, such as nicorandil or metformin, which can sometimes irritate the digestive tract. Alternatively, diabetes can sometimes cause nerve-related burning, which might require adjusting your pregabalin or amitriptyline. Please share this with your doctor so they can safely review your medication plan.