Early Recognition: Functional dyspepsia symptoms have been noted for centuries, often grouped with general indigestion.

20th Century Developments: Advances in gastroenterology, particularly endoscopy, helped differentiate between organic causes and symptoms without visible abnormalities, leading to the term 'non-ulcer dyspepsia.'

Terminology Evolution: The term 'functional dyspepsia' was adopted to highlight dysfunction rather than structural disease.

Modern Understanding: Research now focuses on factors like altered gut motility and psychological influences, with diagnostic criteria such as the Rome criteria standardizing diagnosis.