For dark facial pigmentation (likely melasma or sunspots), your wife should consult a dermatologist for a proper diagnosis. Commonly prescribed medicated creams contain active ingredients like Hydroquinone (a skin-lightening agent), Tretinoin (a retinoid to boost cell turnover), or Azelaic Acid. Often, a dermatologist-prescribed 'triple combination cream' works best. Over-the-counter options containing Vitamin C, Kojic Acid, or Niacinamide can also help. Most importantly, she must apply a broad-spectrum sunscreen (SPF 30 or higher) daily, as UV exposure worsens pigmentation and makes treatments ineffective. Avoid using strong steroid creams without medical supervision.

Dark patches on the face in a 45-year-old woman are most commonly due to conditions like melasma, sun-related pigmentation, or post-inflammatory pigmentation, and the treatment depends on the exact cause. The most important step is strict sun protection using a good sunscreen every day, wearing a scarf or hat outdoors, and avoiding direct sun exposure as much as possible, because the sun is the main trigger for worsening pigmentation. Topical treatments prescribed by a dermatologist, such as depigmenting creams (for example, combinations containing hydroquinone, retinoids, or azelaic acid), can gradually lighten the patches when used correctly. Chemical peels or laser treatments may also be options in stubborn cases under specialist care. It is also helpful to check for contributing factors like hormonal changes or thyroid issues if pigmentation is widespread or worsening. Since many treatments need supervision, it is best to consult a dermatologist for proper diagnosis and a safe, tailored treatment plan.

Apply a thin layer of Melalite Forte cream to the affected areas with clean, dry hands, and gently massage it into the skin. Use only a small pea-sized amount or the quantity advised by your doctor. Avoid contact with the eyes and mouth.

To treat hyperpigmentation and dark spots, a combination of sun protection and targeted topical ingredients is most effective. First, apply a broad-spectrum sunscreen (SPF 30+) daily, as UV light prevents healing. For active treatments, look for creams containing: 1. Hydroquinone (2-4 percent): The gold standard for fading spots (use short-term under medical guidance). 2. Retinoids (Tretinoin or Retinol): To speed up cell turnover. 3. Brighteners: Azelaic acid, Kojic acid, Vitamin C, or Niacinamide, which inhibit pigment production. 4. AHAs (Glycolic acid): To exfoliate dark surface cells. Always introduce new products gradually, and consult a dermatologist for a tailored prescription regimen.

You may use creams containing skin-lightening agents such as mild hydroquinone, kojic acid, or niacinamide. Apply only to the affected areas, use sunscreen on exposed skin, and avoid long-term unsupervised use. Please consult your doctor before using these creams to rule out any underlying conditions.

There is no conclusive evidence that Melalite Forte Cream (Hydroquinone) causes skin cancer in humans. However, prolonged use may cause sun sensitivity, skin thinning, irritation, dryness, and ochronosis (a permanent bluish-black skin discolouration). Use only as prescribed and avoid long-term unsupervised application.