Furosemide+spironolactone
About Furosemide+spironolactone
Furosemide+spironolactone used to treat oedema. It effectively reduces excess fluid levels in the body and treats oedema (swelling) associated with heart, liver, kidney, or lung disease.
Furosemide+spironolactone works by increasing the amount of urine that is passed out from the kidneys. Thus, it lowers high blood pressure and reduces the risk of heart attack, stroke, or chest pain.
In some cases, Furosemide+spironolactone may cause side effects such as low blood pressure (hypotension), dehydration, electrolyte disturbances (potassium and sodium), headache, nausea, or dizziness. Most of these side effects do not require medical attention. However, talk to your doctor if you experience these side effects persistently.
Inform your doctor if you are suffering from any kidney, liver or heart disease. If you are pregnant or breastfeeding, please tell your doctor. Reducing the amount of table salt (sodium chloride) in your diet often relieves body swelling.
Uses of Furosemide+spironolactone
• Edema Treatment: Furosemide+spironolactone helps to treat edema by reducing excess fluid accumulation in the body's tissues, often associated with conditions like heart failure, liver cirrhosis, or kidney disorders.
• Hypertension Management: Furosemide+spironolactone is used as an adjunct therapy to help manage hypertension by lowering blood pressure.
• Potassium-Sparing Diuretic: Furosemide+spironolactone is a potassium-sparing diuretic that helps the body get rid of excess water and sodium while retaining potassium, supporting electrolyte balance.
• Congestive Heart Failure: Furosemide+spironolactone helps to manage congestive heart failure by reducing fluid retention, alleviating symptoms, and improving quality of life and physical activity for patients.
• Improvement in heart and kidney function: Furosemide+spironolactone helps to improve heart and kidney function by reducing excess fluid in the body, preventing complications like swelling, shortness of breath, and strain on the heart and kidneys.
Medicinal Benefits
- Furosemide+spironolactone is used to treat oedema (fluid retention).
- It helps the body lose excess fluids by increasing urine production.
- Reduces swelling (oedema) associated with heart, liver, kidney, or lung disorders.
- Maintains potassium balance in the body.
Directions for Use
- Take Furosemide+spironolactone with or without food as advised by your doctor.
- Follow your doctor’s instructions on the dosage and timing of this medication to ensure safe and effective use.
- Swallow Furosemide+spironolactone as a whole with a glass of water.
- Do not crush, chew, or break it.
Storage
Side Effects of Furosemide+spironolactone
- Electrolyte disturbances
- Dehydration
- Hyponatremia (low sodium concentration in the blood)
- Hypochloraemia (low blood levels of chloride)
- Hypokalaemia (low potassium levels)
- Increased blood cholesterol
- Increased uric acid
- Low blood pressure (hypotension)
- Orthostatic hypotension
- Increased urine volume
- Headache
- Drowsiness/somnolence
Drug Warnings
- Furosemide+spironolactone should not be given to people allergic to any of its components, who have low blood pressure (less than 90 mmHg), have had a heart attack, have kidney disease (with creatinine clearance less than 30 mL/min), have liver disease, or are pregnant or breastfeeding.
- Furosemide+spironolactone is contraindicated in low blood pressure (hypotension), cardiogenic shock (sudden stopping of blood flow to the heart), and aortic stenosis (heart valve problem).
- Furosemide+spironolactone may cause vocal changes, so special attention must be given to the patients using Furosemide+spironolactone and whose voice is significant for their work (like actors, singers, or teachers).
- Hypovolaemia or dehydration with electrolyte and acid-base disturbances must be corrected before using Furosemide+spironolactone.
- Try not to stop taking Furosemide+spironolactone on your own, as doing so may raise your blood pressure, thereby increasing the risk of getting heart disease and stroke.
Drug Interactions
Drug-Drug Interactions: Furosemide+spironolactone may interact with other high blood pressure-lowering pills (metoprolol, ramipril, hydrochlorothiazide, atorvastatin), and it can lower your blood pressure, leading to a severe condition. Besides this, it also interacts with medicine to treat erectile dysfunction (sildenafil), anti-epilepsy medicines (carbamazepine, phenobarbital), immune-suppressing drugs (cyclosporine), and painkillers (ibuprofen, aspirin) etc.
Drug-Food Interactions: You are recommended not to consume alcohol along with Furosemide+spironolactone to avoid unpleasant side effects.
Drug-Disease Interactions: Furosemide+spironolactone should not be given to the people with cardiogenic shock (when the heart fails to pump required blood to the body), heart valve problem (stenosis), low blood pressure (hypotension), coronary heart disease, liver disease, or heart failure, low serum potassium (hypokalemia), and patients with nil urine output (anuria).
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
cautionYou are recommended not to consume alcohol along with Furosemide+spironolactone to avoid unpleasant side effects.
Pregnancy
unsafeFurosemide+spironolactone must not be taken during pregnancy.
Breast Feeding
unsafeBreastfeeding must be avoided during treatment with Furosemide+spironolactone.
Driving
unsafeIt is not recommended to drive after taking Furosemide+spironolactone as it may occasionally cause drowsiness due to orthostatic hypotension (sudden drop in blood pressure on standing from a lying position).
Liver
cautionFurosemide+spironolactone to be taken with caution, especially if you have a history of liver diseases/conditions. Your doctor may adjust your dose depending upon your current liver conditions.
Kidney
cautionFurosemide+spironolactone to be taken with caution, especially if you have a history of Kidney diseases/conditions. Your doctor may adjust your dose depending upon your current kidney conditions.
Children
unsafeFurosemide+spironolactone is not recommended for children below 12 years of age.
Habit Forming
Diet & Lifestyle Advise
- Consume antioxidant-rich food. Blueberries, cherries, tomatoes, squash, and bell peppers are high in antioxidants.
- Eat natural diuretic foods. Asparagus, beets, green beans, grapes, onion, leafy greens, pineapple, leeks, pumpkin, and garlic are all-natural diuretic foods.
- Use healthy cooking oils like soybean, olive, canola, and coconut oil.
- You should avoid refined foods such as white bread, spaghetti, sugar, and red meat.
- Reduce or eliminate Trans fatty acids, which are found in commercially baked items such as cookies, cakes, crackers, French fries, onion rings, doughnuts, and processed foods.
- Avoid consumption of too much salt or salty food.
- Keep your weight under control with a BMI of 19.5-24.9.
- Regular physical activity or exercise, like walking, improves your blood flow.
- When possible, elevate your legs or the swollen area on a chair or pillows.
- Avoid standing or sitting for extended periods of time.
- Avoid chronic stress, as it can raise your blood pressure.
- Spend time with your loved ones to cope with stress and practice mindfulness techniques.
- Quitting smoking and alcohol consumption is the best strategy to lower the risk of many health complications.
Special Advise
- Treatment with Furosemide+spironolactone requires regular monitoring of serum potassium, sodium, and creatinine levels.
Patients Concern
Disease/Condition Glossary
Oedema: Oedema, also known as fluid overload, occurs due to the build-up of fluid in spaces between the cells. Oedema can result from a variety of factors. Some oedema reasons are caused by your lifestyle, while others are caused by an underlying medical problem. Shortness of breath, chest pain (angina), abnormal heart rhythms (arrhythmia), and swelling in the hands or abdominal areas are the symptoms of oedema.
FAQs
Furosemide+spironolactone is used to treat hypertension (high blood pressure and oedema (fluid retention). It helps to remove excess water from the body.
Furosemide+spironolactone works by increasing the amount of urine that is passed out from the kidneys. It effectively reduces excess fluid levels in the body and treats oedema (swelling) associated with heart, liver, kidney, or lung disease.
No, you are advised to inform your doctor and monitor your blood pressure for at least two weeks before stopping the medicine. Depending upon your current blood pressure readings, there is a possibility your doctor may lower your medicine dosage and not recommend discontinuing it.
You should closely monitor your blood pressure, renal function and electrolytes within 4-6 weeks of commencing therapy. Besides this, frequent checks of the potassium level are required in patients with kidney failure and with creatinine clearance below 60 ml/min.
If your leg (foot, ankle) or any other body part is swelling, you need to visit a physician or cardiologist who could perform an ultrasound examination of your leg veins and an ultrasound of your heart (echocardiogram-ECG).
Store Furosemide+spironolactone at room temperature, in a dry place. Keep out of sight and reach of children.
Do not take Furosemide+spironolactone if you are allergic to any of its components, have low blood pressure (less than 90 mm of Hg), have had a heart attack, or have kidney disease (with creatinine clearance less than 30 mL/min). Besides this, it is contraindicated in cardiogenic shock (sudden stopping of blood flow to the heart), and aortic stenosis (heart valve problem).
Furosemide+spironolactone is a combination medicine used to treat oedema (fluid overload) and hypertension (high blood pressure).
Yes, Furosemide+spironolactone is safe if taken in the dose and duration prescribed by the doctor.
Furosemide+spironolactone may cause dizziness as a side effect. Do not drive or operate machinery if you experience dizziness.
Furosemide+spironolactone contains furosemide which may increase uric acid levels leading to gout. Consult the doctor if you experience sudden severe pain in a joint (usually your big toe).
