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Diclofenac+paracetamol

About Diclofenac+paracetamol

Diclofenac+paracetamol is used to treat acute musculoskeletal pain and inflammatory conditions like osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis. Pain is not a disease but a signal from the nervous system that causes uncomfortable sensations in the body.

Diclofenac+paracetamol contains Diclofenac and Paracetamol, which work together to reduce pain and swelling in the body. It helps relieve joint and muscle pain by easing inflammation and discomfort. It also reduces fever and provides effective relief from aches, including toothache, ear pain, and back pain.

Diclofenac+paracetamol can be taken with or after the meal. Diclofenac+paracetamol may cause common side effects such as stomach upset, dizziness, lightheadedness, malaise (weakness), nausea, vomiting, liver dysfunction (hepatitis), pruritus (itchy skin), and rash. Most of these side effects do not require medical attention. However, talk to your doctor if you experience these side effects persistently.

Keep your doctor informed about your health condition and ongoing medicines to rule out any side effects/interactions. Diclofenac+paracetamol is not recommended during the last three months of pregnancy and for children. Inform your doctor if you are pregnant or breastfeeding before taking Diclofenac+paracetamol.

Uses of Diclofenac+paracetamol

Diclofenac+paracetamol is used in the treatment of Pain relief (Musculoskeletal pain, Osteoarthritis, Rheumatoid arthritis, Ankylosing spondylitis). The detailed uses of Diclofenac+paracetamol are as follows: • Musculoskeletal Pain: Diclofenac+paracetamol is effective for back pain, sprains, strains, and joint pain. • Arthritis (Rheumatoid, Osteoarthritis and Ankylosing Spondylitis): Diclofenac+paracetamol reduces inflammation and stiffness in joints. • Headache & Migraine: Diclofenac+paracetamol eases mild to moderate headaches and tension-type migraines. • Dental Pain: Diclofenac+paracetamol is used after dental procedures or for toothaches. • Menstrual Cramps (Dysmenorrhea): Diclofenac+paracetamol relieves lower abdominal pain during periods.

Medicinal Benefits

Diclofenac+paracetamol, when used as prescribed, may provide the following benefits:

For Musculoskeletal Pain:

  • Helps relieve back pain, joint pain, sprains, and strains.
  • Eases headache, migraine, and dental pain.
  • Reduces lower abdominal pain during menstrual cramps.
  • Improves comfort during daily activities.

For Inflammation Associated with Musculoskeletal Conditions:

  • Helps reduce joint swelling and stiffness in arthritis conditions.
  • Improves flexibility and ease of movement.
  • Reduces inflammation-related discomfort in long-term joint problems

Directions for Use

  • Take Diclofenac+paracetamol, with or without food, as advised by your physician.
  • Follow your doctor’s instructions on the dosage and timing of this medication to ensure safe and effective use.
  • Swallow Diclofenac+paracetamol as a whole with a glass of water.
  • Do not crush, chew, or break it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Diclofenac+paracetamol

  • Dizziness
  • Light-headedness
  • Malaise (feeling of discomfort)
  • Nausea
  • Vomiting
  • Liver dysfunction

Drug Warnings

  • Do not take Diclofenac+paracetamol if you are allergic to any components present in it.
  • Patients with asthma, prolonged bleeding time, wheezing (a whistling sound during breathing), and airway obstruction (bronchospasm) should avoid using Diclofenac+paracetamol.
  • It is not recommended for use in children less than 14 years of age and people with liver disease, heart disease, or gastric ulcers/bleeding problems.
  • Diclofenac+paracetamol may be associated with a slight increase in the risk of heart attack (myocardial infarction).
  • Pregnant women should not take it during their last trimester of pregnancy.
  • Diclofenac+paracetamol is excreted in the breast milk, so the nursing mother should contact the doctor before its usage.
  • Avoid the consumption of alcohol, as it may damage your liver and cause even more side effects when taking this drug.
  • Diclofenac+paracetamol is contraindicated if you experience symptoms like tightness of the chest, breathing difficulties, fever, skin rashes, increased heart rate, or any signs of hypersensitivity.
  • Consult your physician if your pain, inflammation, and fever persist after 10 days.

Drug Interactions

Drug-Drug Interaction: Inform your doctor if you are taking any other medicines, as there may be an interaction.

Pain-relief  medicines – NSAIDs (Meloxicam, Valdecoxib)
Potential effect: May increase the risk and severity of gastrointestinal irritation, ulcers, and bleeding.

Anaesthetic - (Ketamine)
Potential effect: May reduce the clearance of ketamine, leading to higher blood levels and increased side effects.

Cholesterol-lowering medicines (Mipomersen, Lomitapide)
Potential effect: May increase the risk and severity of liver injury.

Anti-anxiety medicine (Oxazepam)
Potential effect: May slow down excretion of oxazepam, leading to increased blood levels and excessive sedation.

Immunity-lowering medicines (Leflunomide, Teriflunomide, Tacrolimus)
Potential effect: May increase the risk and severity of kidney and liver problems.

Antifungal medicine (Ketoconazole)
Potential effect: May increase the risk of liver injury.

Anticancer medicines (Dasatinib, Ramucirumab)
Potential effect: May increase the risk of bleeding.

Anti-HIV medicines (Tenofovir disoproxil, Tenofovir alafenamide)
Potential effect: May increase the risk of developing kidney problems.

Blood-thinning medicine – Anticoagulant (Dabigatran etexilate)
Potential effect: May increase the risk of stomach and gastrointestinal bleeding.

Drug-Food Interactions:

Alcohol: Avoid excessive alcohol intake while taking Diclofenac+paracetamol, as it may irritate the stomach and increase side effects.

Drug-Disease Interactions: Inform your doctor if you are suffering from any of these conditions.

  • Asthma
  • Urticaria or acute rhinitis
  • Gastric or intestinal ulcer
  • severe liver, kidney or heart problems
  • Blood disorders
  • Phenylketonuria (an inherited condition that causes a build-up of phenylalanine (an amino acid) in the blood).

Drug-Drug Interactions Checker List:

  • MELOXICAM
  • VALDECOXIB
  • KETAMINE
  • MIPOMERSEN
  • LOMITAPIDE
  • OXAZEPAM
  • LEFLUNOMIDE
  • TERIFLUNOMIDE
  • TACROLIMUS
  • KETOCONAZOLE
  • DASATINIB
  • RAMUCIRUMAB
  • TENOFOVIR DISOPROXIL
  • TENOFOVIR ALAFENAMIDE
  • DABIGATRAN ETEXILATE
  • Safety Advice

    • Safety Warning

      Alcohol

      caution

      Avoid excessive alcohol consumption, as drinking too much alcohol may irritate your stomach.

    • Safety Warning

      Pregnancy

      unsafe

      Diclofenac+paracetamol is not recommended for use in the last three months of pregnancy as it may harm the unborn child or cause problems at delivery. Hence, if you are pregnant or planning pregnancy, inform your doctor before taking Diclofenac+paracetamol. Your doctor may prescribe this medicine if the benefits outweigh the risks.

    • Safety Warning

      Breast Feeding

      caution

      If you are breastfeeding, inform your doctor before taking the Diclofenac+paracetamol. Your doctor may prescribe this medicine if the benefits outweigh the risks.

    • Safety Warning

      Driving

      unsafe

      Diclofenac+paracetamol may affect driving ability by causing headaches, blurred vision, dizziness, or drowsiness.

    • Safety Warning

      Liver

      consult your doctor

      If you have a history of liver disease, inform your doctor before taking Diclofenac+paracetamol. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

    • Safety Warning

      Kidney

      consult your doctor

      If you have a history of kidney diseases, inform your doctor before taking Diclofenac+paracetamol. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

    • Safety Warning

      Children

      unsafe

      Diclofenac+paracetamol is not recommended for children below 14 years. For children older than 14 years, this medicine may be administered if a doctor has prescribed it.

    Habit Forming

    No

    Diet & Lifestyle Advise

    Physical Activity:

    • Engage in gentle exercises such as walking or swimming for 20–30 minutes to reduce joint stiffness.
    • Practice yoga to improve flexibility and pain control.
    • Stretch regularly to keep joints mobile

    Weight Management:

    • Maintain a healthy weight with low-strain exercises.
    • Follow a balanced diet to reduce joint stress.

    Rest & Recovery:

    • Get enough sleep to help muscles and joints heal.
    • Take short rest breaks during the day to avoid overuse.

    Pain Relief Measures:

    • Use heat or cold packs on joints for 15–20 minutes.
    • Maintain proper posture while sitting or sleeping

    Stress Management:

    • Reduce stress through meditation, reading, or calming music.
    • Relaxation helps lower pain flare-ups

    Supportive Therapies:

    • Acupuncture, massage, or physiotherapy may improve comfort

    Diet Choices:

    • Eat antioxidant-rich foods like berries, spinach, and beans.
    • Include flavonoid-rich foods such as broccoli, grapes, soy, and green tea.
    • Drink enough water to support joint health.

    Habits:

    • Avoid smoking and alcohol to prevent worsening of joint symptoms.

    Patients Concern

    Disease/Condition Glossary

    Pain: Pain is a symptom triggered by the nervous system, causing uncomfortable sensations in the body. Pain may be dull or sharp; it may be constant or intermittent. Tolerance for pain varies from person to person. Pain can be generalised (affecting the whole body) or localised (affecting a specific area). The common causes of pain include headache, muscle strain, cramps, fractures, arthritis, and injury.

    Musculoskeletal pain: It is generally caused by disorders of bones, joints, muscles, tendons, ligaments, or a combination. Injuries (mostly sports-related) are the most common cause of musculoskeletal pain. Muscle pain (myalgia) can be caused by injury, infection, loss of blood flow to the muscle, or a tumour. Extreme tissue pain and inflammation resulting from sprains, strains, trauma, or postoperative procedures may require prolonged healing.

    FAQs

    Diclofenac+paracetamol is used to relieve pain associated with musculoskeletal joint conditions like osteoarthritis, rheumatoid arthritis and ankylosing spondylitis.

    Diclofenac+paracetamol contains Diclofenac (analgesic) and Paracetamol (fever reducer/mild analgesic), effective against painful musculoskeletal pain, joint pain, and skeletal muscle spasms. Diclofenac works by inhibiting pain and inflammation at the site of injury or damage. Paracetamol acts as a mild analgesic (pain reducer) and antipyretic (fever reducer), enhancing the Analgesic and antipyretic effects of diclofenac.

    No, Diclofenac+paracetamol is not indicated for stomach pain. Additionally, if you experience post-ingestion abdominal pain, it may indicate a gastric ulcer or bleeding. Do not take Diclofenac+paracetamol in this condition. It is advisable to inform your doctor if you experience stomach pain after ingesting this medication.

    No, do not take Diclofenac+paracetamol until prescribed by your doctor. For example, your shoulder pain may be due to lung, spleen, or gallbladder problems. Your back pain may be due to kidney stones, pancreas swelling, or, in women, pelvic disorders. Your arm pain (especially the left arm) may be due to a heart attack (myocardial infarction).

    Yes, Diclofenac+paracetamol is a short-term medication, and if you feel better, you can stop taking Diclofenac+paracetamol, but only after consulting your doctor.

    Yes, the long-term use of Diclofenac+paracetamol can cause damage to the kidneys.

    No, Diclofenac+paracetamol is not addictive, but it's important always to take it as prescribed.

    No, Diclofenac+paracetamol should not be taken as a long-term medication as it may lead to stomach ulcers/bleeding and kidney problems. For the best results of Diclofenac+paracetamol, take it in doses and duration mentioned by your doctor.

    Before taking Diclofenac+paracetamol, inform your doctor about your medical history, allergies, and medications. This medication is not recommended for children, pregnant or breastfeeding women, or people with stomach ulcers or kidney or liver disease. Always follow the recommended dosage and monitor your blood pressure regularly. Read the label carefully and consult your doctor for any questions or concerns.

    Diclofenac Paracetamol is not suitable for children under 14 years old. A doctor's guidance is necessary for teenagers between 14 and 18 to determine the correct dosage and treatment duration.

    Diclofenac+paracetamol is a combination medication primarily used for the treatment of various types of pain, including Musculoskeletal pain, Osteoarthritis, Rheumatoid arthritis, and Ankylosing spondylitis. It contains two active ingredients: Diclofenac and Paracetamol.

    Diclofenac+paracetamol is a safe and effective medication when used as directed. However, it's essential to be aware of potential side effects and take steps to minimize risks. Common side effects are usually mild and may include stomach upset, diarrhoea, headache, and dizziness. In rare cases, more serious issues can occur, such as stomach ulcers, kidney damage, or allergic reactions. To ensure safe use, always follow the recommended dosage, inform your doctor about your medical history and any other medications you're taking, and monitor your health closely.

    Yes, the use of Diclofenac+paracetamol can cause nausea and vomiting in some individuals. These side effects usually fade away with time. Making some lifestyle changes, such as eating smaller meals or avoiding triggers, can also help alleviate symptoms. However, consult your doctor for further guidance and support if nausea and vomiting persist or worsen.

    Yes, the use of Diclofenac+paracetamol causes dizziness in some individuals. This side effect is usually mild and temporary, but it can be a concern, especially for people who need to drive, operate heavy machinery, or perform other activities that require attention and balance. If you experience dizziness, get up slowly, avoid driving or operating heavy machinery, and hold onto something stable for support. Usually, dizziness caused by Diclofenac Paracetamol fades away with time. However, if the dizziness is severe, persists, or worsens, consult your doctor for further guidance and support.

    Yes, the use of Diclofenac+paracetamol can potentially cause damage to the kidneys in some individuals, especially with long-term or high-dose use. This risk is higher in people with pre-existing kidney problems or those taking other medications that can harm the kidneys. However, by making healthy diet and lifestyle changes, taking medication as directed by your doctor, and undergoing regular monitoring, you can minimize this risk and protect your kidney health.

    There are specific contraindications associated with the use of Diclofenac+paracetamol. Individuals with a known hypersensitivity to Diclofenac, Paracetamol, or other NSAIDs should avoid taking this medication. Additionally, it is contraindicated in patients with active peptic ulcer or bleeding, severe kidney or liver impairment, heart failure, or coronary artery disease. Pregnant women, especially in the third trimester, and breastfeeding mothers should also consult their doctor before taking Diclofenac Paracetamol. Furthermore, concomitant use of other NSAIDs or anticoagulants is not recommended.

    Exercise caution when considering taking Diclofenac+paracetamol with Vitamin B-complex. While there may not be a known interaction, it's essential to consult your doctor or pharmacist before combining these medications. Do not take Diclofenac+paracetamol with Vitamin B-complex unless advised by your doctor, who can assess potential interactions and provide personalized guidance based on your specific health needs and medications.

    No, taking a higher dose than the recommended dose of Diclofenac+paracetamol is unsafe. Taking more than the prescribed dose can increase the risk of serious side effects, including stomach ulcers, bleeding, kidney damage, and liver damage. Always follow your doctor's instructions and take the medication as directed. If you experience inadequate pain relief or have concerns about your dosage, consult your doctor for guidance. Never exceed the recommended dose without consulting your doctor.

    The recommended storage condition for Diclofenac+paracetamol is to keep it in a cool and dry place away from direct sunlight. Additionally, keep it out of children's sight and reach to prevent accidental ingestion.

    It's generally not recommended to take Diclofenac Paracetamol while breastfeeding, as the medication may pass into breast milk and potentially harm the nursing infant. If you're breastfeeding and experiencing pain, consult your doctor or pharmacist for guidance on safe and alternative pain management options.

    Diclofenac+paracetamol may cause common side effects, including stomach upset, dizziness, nausea, vomiting, liver dysfunction, pruritus, and rash. Most of these side effects are mild and resolve spontaneously. However, consult your doctor for further guidance and care if they persist or worsen.

    Taking other medicines with Diclofenac+paracetamol without consulting your doctor first is not recommended. Some medications can interact with Diclofenac+paracetamol, increasing the risk of adverse effects. Inform your doctor about all the medications you're currently taking, including prescription, over-the-counter, and herbal supplements, to ensure safe and effective treatment.

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    Diclofenac+paracetamol

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